参附注射液建立自发性高血压病大鼠肝阳上亢证模型的研究          下载免费PDF全文

周梦  杨文丽  刘晓庆 《应用海洋学学报》2018,34(12):120-122

目的：探讨参附注射液建立自发性高血压大鼠（SHR）模型的可能性。方法：将30只3月龄SPF级健康雄性自发性高血压大鼠称重，随机分为SHR组，附子汤组，参附注射液低、中、高剂量组，每组6只。各组采用对应药物灌胃进行模型制备，另取同品系同周龄雄性魏-凯二氏大鼠（WKY）6只作为正常对照组（WKY组）。观察参附注射液对SHR大鼠24h饮水量、易激惹程度、痛阈、睑结膜充血及收缩压的影响。结果：附子汤组及参附注射液中、高剂量组造模后均出现了易激惹程度增高、睑结膜充血程度增高、饮水量增多、痛阈降低、收缩压升高等肝阳上亢的表现，与WKY组及SHR组比较，差异有统计学意义（P<0.05)，表明造模成功。结论：参附注射液可以制备新型高血压肝阳上亢证模型，但是具体造模机制以及造模药物用量需待进一步探讨确定。  相似文献   

Retrieving volume FeO and TiO_2 abundances of lunar regolith with CE-2 CELMS data using BPNN method     

Cai Liu  Hong-Yan Sun  Zhi-Guo Meng  Yong-Chun Zheng  Yu Lu  Zhan-Chuan Cai  Jin-Song Ping  Alexander Gusev  Shuo Hu 《天文和天体物理学研究(英文版)》2019,(5)

The volume FeO and TiO_2 abundances(FTAs) of lunar regolith can be more important for understanding the geological evolution of the Moon compared to the optical and gamma-ray results. In this paper, the volume FTAs are retrieved with microwave sounder(CELMS) data from the Chang'E-2 satellite using the back propagation neural network(BPNN) method. Firstly, a three-layered BPNN network with five-dimensional input is constructed by taking nonlinearity into account. Then, the brightness temperature(TB) and surface slope are set as the inputs and the volume FTAs are set as the outputs of the BPNN network.Thereafter, the BPNN network is trained with the corresponding parameters collected from Apollo, Luna,and Surveyor missions. Finally, the volume FTAs are retrieved with the trained BPNN network using the four-channel TBderived from the CELMS data and the surface slope estimated from Lunar Orbiter Laser Altimeter(LOLA) data. The rationality of the retrieved FTAs is verified by comparing with the Clementine UV-VIS results and Lunar Prospector(LP) GRS results. The retrieved volume FTAs enable us to re-evaluate the geological features of the lunar surface. Several important results are as follows. Firstly, very-low-Ti(1.5 wt.%) basalts are the most spatially abundant, and the surfaces with TiO_2 5 wt.% constitute less than 10% of the maria. Also, two linear relationships occur between the FeO abundance(FA) and the TiO_2 abundance before and after the threshold, 16 wt.% for FA. Secondly, a new perspective on mare volcanism is derived with the volume FTAs in several important mare basins, although this conclusion should be verified with more sources of data. Thirdly, FTAs in the lunar regolith change with depth to the uppermost surface,and the change is complex over the lunar surface. Finally, the distribution of volume FTAs hints that the highlands crust is probably homogeneous, at least in terms of the microwave thermophysical parameters.  相似文献   

Walking Access Distance of Metro Passengers and Relationship with Demographic Characteristics: A Case Study of Nanjing Metro     

Jinliao He  Ruozhu Zhang  Xianjin Huang  Guangliang Xi 《中国地理科学(英文版)》2018,28(4):612-623

In the metropolises of China, the metro plays an increasingly important role in commuting because of its efficiency, affordability, and cleanliness. This paper attempts to explore the relationship between walking access distance to metro stations and the demographic characteristics of passengers, such as age, monthly income, travel frequency, gender, and travel purpose, as well as the influence of the urban context. Nanjing Metro Line 2 is selected as the case study. By using different methods such as a questionnaire survey, spatial decay function, analysis of covariance (ANOVA), network analysis of routes, and K-means cluster analysis, it is suggested that demographic characteristics have a significant impact on the pedestrian walking distance, with the exception of gender. Furthermore, the paper finds a spatial decay effect in walking access distance, the decay rate of which, however, varies across stations. Terminal stations have a larger pedestrian catchment area than in regular and exchange stations. Moreover, the passengers of Nanjing Metro Line 2 can be classified into six groups according to their demographic characteristics, among which education and occupation are vital indicators in determining their willingness to walk to the stations. Middle-class passengers have a higher dependence on the metro and tend to walk longer than other groups do. This study provides an important reference for planners and transport sectors to optimize land-use and transport infrastructures.  相似文献   

Regional Characteristics and Causes of Haze Events in Northeast China     

Weiwei Chen  Shichun Zhang  Quansong Tong  Xuelei Zhang  Hongmei Zhao  Siqi Ma  Aijun Xiu  Yuexin He 《中国地理科学(英文版)》2018,28(5):836-850

Northeast China experiences severe atmospheric pollution, with an increasing occurrence of heavy haze episodes. However, the underlying forces driving haze formation during different seasons are poorly understood. In this study, we explored the spatio-temporal characteristics and causes of haze events in Northeast China by combining a range of data sources(i.e., ground monitoring, satellite-based products, and meteorological products). It was found that the ‘Shenyang-Changchun-Harbin(SCH)'city belt was the most polluted area in the region on an annual scale. The spatial distribution of air quality index(AQI) values had a clear seasonality, with the worst pollution occurring in winter, an approximately oval-shaped polluted area around western Jilin Province in spring, and the best air quality occurring in summer and most of the autumn. The three periods that typically experienced intense haze events were Period I from mid-October to mid-November(i.e., late autumn and early winter), Period II from late-December to February(i.e., the coldest time in winter), and Period III from April to mid-May(i.e., spring). During Period I, strong PM_(2.5) emissions from seasonal crop residue burning and coal burning for winter heating were the dominant reasons for the occurrence of extreme haze events(AQI 300). Period II had frequent heavy haze events(200 AQI 300) in the coldest months of January and February, which were due to high PM_(2.5) emissions from coal burning and vehicle fuel consumption, a lower atmospheric boundary layer, and stagnant atmospheric conditions. Haze events in Period III, with high PM_(10) concentrations, were primarily caused by the regional transportation of windblown dust from degraded grassland in central Inner Mongolia and bare soil in western Jilin Province. Local agricultural tilling could also release PM_(10) and enhance the levels of windblown dust from tilled soil. Better control of coal burning, fuel consumption, and crop residue burning in winter and autumn is urgently needed to address the haze problem in Northeast China.  相似文献   

On the electron density diagnostics of silicon <Emphasis Type="SmallCaps">viii</Emphasis> ion in solar transition region     

Jian He  Qingguo Zhang 《Astrophysics and Space Science》2018,363(9):194

The conditions for accurate electron density diagnostics in the solar transition region are discussed, and result shows that lines from Si?viii can provide an excellent tool for electron density diagnostics of the emitting plasma. For the Si?viii 1440.50 Å and 1445.75 Å lines, the principle of the electron density diagnostics is discussed for any intensity ratio. By the observed intensity ratio, the diagnostic results of the electron density for the quiet sun and the active region are calculated, and results indicate that in the quiet sun, the averaged electron density is \(\log (N_{e}) = 8.63\); while in the active region, the averaged density gets the maximum \(\log (N_{e}) = 8.86\) in the active region (B), and gets the minimum \(\log (N_{e}) = 8.38\) in the active region (E), where the electron density is in the unit of cm^?3. Finally, the relationship of intensity ratio and electron density is discussed, in the case of lower and higher electron density limits. This discussion is significant in the electron density diagnostics, which will be important for study on coronal heating and acceleration of solar wind.  相似文献   

基于概率积分法的采动坡体稳定性预测与分析          下载免费PDF全文

王猛  孙丽丽  薄怀志 《山东国土资源》2018,34(12)

地下采煤会引起地表沉降、变形,甚至引发山体、河堤滑坡等地质灾害。采动坡体的稳定性研究一直是采矿工程中实际关心的问题。该文首先介绍分析了概率积分法移动变形稳态、动态预测模型以及基于极限平衡理论的单滑面采动坡体稳定性预测模型,提出了使用概率积分法结合Knothe时间函数对采动坡体稳定性进行预测分析的方法,并使用C#及XML Schema语言编制了相关的计算程序。最后,结合一个工程实例对采动坡体稳定性和动态变化过程进行了预测与分析,通过实测数据验证了提出方法的可行性,得出了采动引起的坡体下沉是影响坡体稳定性的主要因素,并提出了在坡体拉伸阶段进行注浆加固的方法。  相似文献   

广西土壤有机质空间变异特征及其影响因素研究   总被引：2，自引：0，他引：2  

钟聪  李小洁  何园燕  邱微文  李杰  张新英  胡宝清 《地理科学》2020,40(3):478-485

基于广西第二次土壤普查的270个土壤剖面资料,结合1∶50万数字化土壤类型图、土地利用类型图和气象监测数据等资料,利用地统计学和逐步回归分析等方法对广西表层土壤有机质空间变异特征及其影响因素进行了探究。结果表明：广西表层土壤有机质平均含量为3.11±2.19%,变异系数为70.72%,空间分布呈北高南低的趋势。广西表层土壤有机质空间分布受到自然和人为因素的共同影响,土壤类型、成土母质、海拔、土地利用、气候和坡度6个环境因子对全区土壤有机质含量变异的综合解释能力为47.9%。其中,土壤类型是最重要的影响因素,能独立解释其变异的36.0%,海拔和成土母质分别能独立解释28.5%和15.8%。气温对广西土壤有机质空间分布的影响比降水量更加显著,从而造成了广西土壤有机质整体呈南低北高的趋势。同时,土壤有机质对气温的敏感性在一定程度上受到降雨量的制约。此外,研究区农业耕作管理等因素对土壤有机质的影响也不容忽视。  相似文献   

GDJ人卫目视观测数据采集和处理系统的研制     

何妙婵 《天文研究与技术》1996,(1)

本文介绍了ＧＤＪ跟踪打印经纬仪在人造卫星的观测中如何应用计算机对多圈卫星的目视观测资料进行实时采集、处理等工作过程的原理和方法。  相似文献   

Preliminary investigation of mercury in bone tissues of skua and penguin in Antarctica using AFS and Synchrotron Radiation X-ray Fluorescence （SR-XRF）   总被引：1，自引：0，他引：1  

谢周清程邦波  孙立广黄宇营 何伟 《极地研究(英文版)》2005,16(1):33-40

Mercury （Hg） was investigated in bone tissues of skua （ Catharacta maccormick） and penguin （Pygoscelis adeliae） collected in the maritime Antarctic using atomic fluorescence spectrometry （AFS） and synchrotron radiation X-ray fluorescence （SR-XRF） method. The total levels of mercury in bone tissues of penguin and skua are much lower than those in other organs （e. g. , kidney, liver）. The toxic effects of mercury in bone tissues of seabirds in polar region are not known. We have used SR- XRF method to map the distribution of trace levels of mercury in bones. The levels of mercury are found to be enriched somewhere near the periosteal surface and/or endosteal surface. The distribution of mercury shows strongly correlation with that of some essential elements and probably poses negative effect on the bone metabolism inferring from the relationship of mercury with the other elements. These studies represent a first step toward understanding the toxic effects of mercury on bone of polar animals by suggesting the possible microscopic investigation.  相似文献   

The relationship between the semi-major axis, mass index and age of the Leonid meteor shower     

Huan Meng 《Monthly notices of the Royal Astronomical Society》2005,359(4):1433-1436

Owing to sublimation of ice, comet nuclei eject dust particles when they are near to the sun. Those particles assume velocities and then vary their orbits to ones similar to that of the comet. The most notable difference between the orbit of the parent comet and those of the particles is their semi-major axes. This difference (Δ a ) has been widely used in modern meteor shower predictions. Observational evidence of the distribution showed that it is a function of Δ a , and the age of the dust trail. However, the relation is not well known. In this paper, a simplified relation between Δ a , the mass index ( s ) and the age of the dust trail is presented, taking the instance of a recent Leonid meteor shower.  相似文献